Can a Personalized Diet Alleviate Depression Symptoms and Improve Digestive Health? Here’s What Researchers Found!
- Judah Elishah M. Cagas
- Feb 13
- 3 min read
Updated: Feb 21
A personalized, high-quality diet rich in fruits, vegetables, and other nutrient-dense foods is associated with a reduction in depressive symptoms and an improvement in quality of life.

What we eat plays a crucial role in both our mental well-being and gut health. Certain eating habits can contribute to depression by increasing inflammation and stress in the body. Adopting a healthier diet may help reduce these symptoms and improve overall well-being.
The researchers of this study set out to examine how a 6-month personalized Mediterranean diet impacts depression symptoms, quality of life, and gut health in older adults. The study included 37 community-dwelling adults (60 years or older), and the intervention involved regular visits from a dietitian, who provided tailored dietary recommendations based on the Mediterranean Diet. During the 6-month study, participants completed surveys on their mood, quality of life, and eating habits and provided stool samples to check gut health.
The results showed that:
A Mediterranean-based personalized diet was associated with a reduction in depression symptoms and improvement in quality of life among older adults.
"The positive changes in mood were associated with increased consumption of certain dietary components related to brain function and mood regulation." (Magzal et al., 2023)
There were significant increases in certain nutrients (folate, lutein, and zeaxanthin) following the personalized diet intervention. Mediterranean diet foods are rich in these nutrients, which help improve gut health and regulate brain chemicals, thereby enhancing mood and emotional stability.
The personalized diet was also associated with a greater variety of healthy gut bacteria. An increase in healthy gut bacteria is often seen as a sign of better overall health. These good bacteria can help improve mood and reduce depression-like symptoms, likely by producing beneficial substances that support brain balance and emotional well-being.
In summary, adopting a healthier diet improves our mental and overall well-being. There is no one-size-fits-all approach when it comes to healthy nutrition, as we have our preferences and each of our body adapts differently. So if the majority of your diet is comprised of healthy foods, keep it up! And if not, you can start by considering incorporating components of the Mediterranean Diet (e.g. vegetables, fruit, nuts, legumes, seeds, fish) into your daily meals.
Note: If you have any existing allergies and medical conditions, seek professional advice from a doctor or other healthcare professionals before changing your diet as certain foods may exacerbate your condition.
Personal Reflection & Action Plan
A personalized, high-quality diet rich in fruits, vegetables, and other nutrient-dense foods is associated with a reduction in depressive symptoms and an improvement in quality of life. Now, whether you are consuming these depends on you. You can start by reflecting on the following:
How often have you eaten fruits, vegetables, nuts, and fish in the past two days?
(1 = Never, 2 = Rarely, 3 = Sometimes, 4 = Often, 5 = Always)
What fruits and vegetables, if any, do you often include in your meals?
You might want to add your favorites, or vegetables like broccoli, kale, spinach, peas, parsley, and corn, to your breakfast for a healthy start.
How can you add more variety to your meals? What are some ways you could combine nutrient-dense foods or prepare your meals differently (e.g., mixing fresh banana slices into your yogurt for breakfast)?
If needed, who can you turn to for professional advice?
For example, you can consult a dietitian, nutritionist, or other trained experts to learn about personalized diet plans.
What existing health conditions do you have or have been diagnosed with? Seek professional advice first from a doctor or other healthcare professionals before proceeding with experimenting with your diet, as certain foods may exacerbate your condition.
Reference: Magzal, F., Turroni, S., Fabbrini, M., Barone, M., Vitman Schorr, A., Ofran, A., & Tamir, S. (2023). A personalized diet intervention improves depression symptoms and changes microbiota and metabolite profiles among community-dwelling older adults. Frontiers in Nutrition, 10. https://doi.org/10.3389/fnut.2023.1234549